Studio One recognizes your PreSonus interface, and preprogrammed templates automatically create software inputs and assign them to the appropriate hardware inputs on your PreSonus interface. You don’t have to configure your software to work with your hardware—Studio One does it for you!
Studio One stores I/O configurations with each song, for each computer, and for each device driver. As a result, you can take a song to a friend’s studio, use Studio One with their interface, and when you get back to your studio, Studio One will recall the original I/O configuration for the song, as if you never left. This works regardless of interface.